発表論文(~2000)
- Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., Nakamura, k. and Taniguchi, T.
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ.
Nature 408, 600-605 (2000). - Hida, S., Ogasawara, K., Sato, K., Abe, M., Takayanagi, H., Yokochi, T., Sato, T., Hirose, S., Shirai, T., Taki, S. and Tanicuhi, T.
CD8+ T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-α/β signaling.
Immunity 13, 643-655 (2000). - Sato, M., Suemori, H., Hata, N., Asagiri, M., Ogasawara, K., Nakao, K., Nakaya, T., Katsuki, M., Noguchi, S., Tanaka, N., and Taniguchi, T.
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-α/β gene induction.
Immunity 13, 539-548 (2000). - Tsujino, S., Di Santo, J. P.,Takaoka, A., Mckernan,T. L., Noguchi, S., Taya, C., Yonekawa, H., Saito, T., Taniguchi, T., and Fujii, H.
Differential requirement of the cytoplasmic subregions of γ c chain in T cell development and function.
Proc. Natl. Acad. Sci. USA 97, 10514-10519 (2000). - Tanaka, N. and Taniguchi, T.
The interferon regulatory factors and oncogenesis.
Sem. Cancer Biol. 10, 73-81 (2000). - Ohki, R., Nemoto, J., Murasawa, H, Oda, E., Inazawa, J., Tanaka, N., and Taniguchi, T.
Reprimo, A new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase.
J. Biol. Chem. 275, 22627-22630 (2000). - Takaoka, A., Mitani, Y., Suemori, H., Sato, S., Yokochi, T., Noguchi, S., Tanaka, N., and Taniguchi, T.
Crosstalk between interferon-γ and-α/β signaling components at caveolar membrane domain.
Science 288, 2357-2360 (2000). - Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita,T., Tokino, T., Taniguchi, T. and Tanaka, N.
Noxa, a BH3-only member of the Bcl-2 family, and candidate mediator of p53-induced apoptosis.
Science 288, 1053-1058 (2000). - Taniguchi, T., Tanaka, N., Ogasawara, K., Taki, S., Sato, M. and Takaoka, A.
The transcription factor IRF-1 and its family members in the regulation of host defense.
Cold Spring Harb. Symp. Quant. Biol. Vol 64, 465-472 (1999). - Taniguchi, T., Tanaka, N., Ogasawara, K., Hida, S., Sato, M. and Takaoka, A.
Regulation of interferon and immune systems by the IRF family of transcription factors.
J. Interferon Cytokine Res. 19(Sup. 1), S55 (1999). - Fujii, Y., Shimizu, T., Kusumoto, M., Kyogoku, Y., Taniguchi, T. and Hakoshima, T.
Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.
EMBO J. 18, 5028-5041 (1999). - Matsumoto, M., Tanaka, N., Harada, H., Kimura, T., Yokochi, T., Kitagawa, M., Schindler, C. and Taniguchi, T.
Activation of the transcription factor ISGF3 by interferong.
Biol. Chem. 380, 699-703 (1999). - Nozawa, H., Oda, E., Nakao, K., Ishihara, M., Ueda, S., Yokochi, T., Ogasawara, K., Nakatsuru, Y., Shimizu, S., Ohira, Y., Hioki, K., Aizawa, S., Ishikawa, T., Katsuki, M., Muto, T., Taniguchi, T., and Tanaka, N.
Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53.
Genes Dev. 13, 1240-1245 (1999). - Takaoka, A., Tanaka, N., Mitani, Y., Miyazaki, T., Fujii, H., Sato, M., Kovarik, P,. Decker, T., Schlessinger, J. and Taniguchi, T.
Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in the IFN-γ, but not IFN-α, signaling.
EMBO J. 18, 2480-2488 (1999). - Sato, M., Hata, N., Asagiri, M., Nakaya, T., Taniguchi, T. and Tanaka, N.
Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7.
FEBS Letters 441, 106-110 (1998). - Fujii, H., Ogasawara, K., Otsuka, H., Suzuki, M, Yamamura, K., Yokochi, T, Miyazaki, T., Suzuki, H., Mak, T. W., Taki, S. and Taniguchi, T.
Functional dissection of the cytoplasmic subregions of the IL-2 receptor βc chain in primary lymphocyte populations.
EMBO J. 17, 6551-6557 (1998). - Nozawa, H., Oda, E., Ueda, S., Tamura, G., Maesawa, C., Muto, T., Taniguchi, T. and Tanaka, N.
Functionally inactivating point mutation in the tumor-suppressor IRF-1 gene identified in human gastric cancer.
Int. J. Cancer 77, 522-527 (1998). - Furui, J., Uegaki, K., Yamazaki, T., Shirakawa, M., Swindells, M. S., Harada, H., Taniguchi, T. and Kyogoku, Y.
Solution structure of the IRF-2 DNA-binding domain: a novel subgroup of the winged helix-turn-helix family.
Structure 6, 491-500 (1998). - Sato, M., Tanaka, N., Hata, N., Oda, E. and Taniguchi, T.
Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-βgene.
FEBS Letters 425, 112-116 (1998). - Miyazaki, T., Takaoka, A., Noguerira, L., Dikic, I., Fujii, H., Tsujino, S., Mitani, Y., Maeda, M., Schlessinger, J. and Taniguchi, T.
Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak-signaling pathway.
Genes Dev. 12, 770-775 (1998). - Ogasawara, K., Hida, S., Azimi, N., Tagaya, Y., Sato, T., Yokochi-Fukuda, T., Waldmann, T.A., Taniguchi, T. and Taki, S.
Requirement of IRF-1 for the microenvironment supporting natural killer cell development.
Nature 391, 700-703 (1998). - Vaughan, P. S., van der Meijden, C. M. J., Aziz, F., Harada, H.,Taniguchi, T., van Wijnen, A. J., Stein J. L. and Stein, G. S.
Cell cycle regulation of histone H4 gene transcription requires the oncogenic factor IRF-2.
J. Biol. Chem. 273, 194-199 (1998). - Tanaka, N., Sato, M., Lamphier, M. S., Oda, E., Schreiber, R. D., Tsujimoto, Y. and Taniguchi, T.
Type I interferons are essential mediators of apoptotic death in virally infected cells.
Genes to Cells 3, 29-37 (1998). - Minami, Y. and Taniguchi, T,
Interleukin-2 and the IL-2 receptor.
Encyclopedia of Human Biology 5, 125-131 (1997). - Kondo, T., Minamino, N., Nagamura-Inoue, T., Matsumoto, M., Taniguchi, T. and Tanaka, N.
Identification and characterization of nucleophosmin/ B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity.
Oncogene 15, 1275-1281 (1997). - Penninger, J.M., Sirard, C., Mittucker, H-W., Chidgey, A., Kozieradzki, I., Nghiem, M., Hakem, A., Kimira, T., Timms, E., Boyd, R., Taniguchi, T., Matsuyama, T. and Mak, T.W.
The interferon refulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes.
Immunity 7, 243-254 (1997). - Fujimura, M., Tominaga, T., Kato, I., Takasawa, S., Kawase, M., Taniguchi, T., Okamoto, H. and Yoshimoto, T.
Attenutation of nitric oxide synthase induction in IRF-1-deficient glial cells.
Brain Res. 759, 247-250 (1997). - Taniguchi, T.
Transcription factors IRF-1 and IRF-2: linking the immune responses and tumor suppression.
J. Cellular Physiology 173, 128-130 (1997). - Taki, S., Sato, T., Ogasawara, K., Fukuda, T., Sato, M., Hida, S., Suzuki, G., Mitsuyama, M., Shin, E.-H., Kojima, S., Taniguchi, T. and Asano, Y.
Multistage regulation of Th1-type immune responses by the transcription factor IRF-1.
Immunity 6, 673-679 (1997). - Endo, A, T., Maruhara, M., Yokouchi, M., Suzuki, Y., Sakamoto, H., Mitsui, K., Matsumoto, A., Taniura, S., Ohtsubo, M., Misawa, H., Miyazaki, T., Nogueira, L., Taniguchi, T., Fujita, T., Kanekura, Y., Komiya, S. and Yoshimura, A.
A new protein containing an SH2 domain that inhibits JAK kinases.
Nature 387, 921-924 (1997). - Taniguchi, T., Lamphier, M. S., and Tanaka, N.
IRF-1: the transcription factor linking the interferon response and oncogenesis.
Biochem. Biophys. Acta. 1333, M9-M17 (1997). - Harada, H., Matsumoto, M., Sato, M., Kashiwazaki, Y., Kimura, T., Kitagawa, M., Yokochi, T., Tan, S-P. R., Takasugi, T., Kadokawa, Y., Schindler, C., Schreiber, R. D., Noguchi, S. and Taniguchi, T.
Regulation of IFN-α/βgenes: evidence for a dual function of the transcription factor complex ISGF3 in the production and action of IFN-α/β.
Genes to Cells 1, 995-1005 (1996). - Adachi, M., Sekiya, M., Torigoe, T., Takayama, S., Reed, J. C., Miyazaki, T., Minami, Y., Taniguchi, T., and Imai, K.
Interleukin-2 (IL-2) upregulates BAG-1 gene expression through serine-rich region within IL-2 receptor βc chain.
Blood 88, 4118-4123 (1996). - Miyazaki, T. and Taniguchi, T.
Coupling of the IL-2 receptor complex with non receptor protein tyrosine kinases.
Cancer Surveys 27, 25-40 (1996). - Tanaka, N., Ishihara, M., Lamphier, M., Nozawa, H., Matsuyama, T., Mak, T.W., Aizawa, S., Tokino, T., Oren, M. and Taniguchi, T.
Cooperation of the tumor suppressors IRF-1 and p53 in response to DNA damage.
Nature 382, 816-818 (1996). - Miyazaki, T., Liu, Z-J. and Taniguchi, T.
Selective cooperation of HTLV-1-encoded p40tax-1 with cellular oncoproeins in the induction of hematopoietic cell proliferation.
Oncogene 12, 2403-2408 (1996). - Tan, S-P. R., Taniguchi, T. and Harada, H.
Identification of the lysyl oxidase gene asa target of the antioncogenic transcription factor, IRF-1, and its possible role in tumor suppression.
Cancer Res. 56, 2417-2421 (1996). - Yamagata, T., Nishida, J., Tanaka, T., Sakai, R., Mitani, K., Yoshida, M., Taniguchi, T., Yazaki, Y. and Hirai, H.
A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes.
Mol. Cell. Biol. 4, 1283-1294 (1996). - Kimura, T., Kadokawa, Y., Harada, H., Matsumoto, M., Sato, M., Kashiwazaki, Y., Tarutani, M., Tan, S-P. R., Takasugi, T., Matsuyakma,T., Mak, W. T., Noguchi, S. and Taniguchi, T.
Essential and non-redundant roles of p48 (ISGF3g) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies.
Genes to Cells 1, 115-124 (1996). - Taniguchi, T., Harada, H. and Lamphier, M.
Regulation of the interferon system and cell growth by the IRF transcription factors.
J. Cancer Res. Clin. Oncol. 121, 516-520 (1995). - Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E. and Matsumoto, K.
Indentification of member of the MAPKKK family as a potential mediator of TGF-βsignal transduction.
Science 270, 2008-2011 (1995). - Taniguchi, T.
IRF-1 and IRF-2 as regulators of the interferon system and cell growth.
Indian J. Biochem. Biophys. 62, 235-239 (1995). - Kawahara, A., Minami, Y., Miyazaki, T., Ihle, J.N., and Taniguchi, T.
Critical role of the interleukin 2 (IL-2) receptor γ-chain-associated Jak3 in the IL-2-induced c-fos and c myc, but not bcl-2, gene induction.
Proc. Natl. Acad. Sci. USA 92, 8724-8728 (1995). - Tamura, T., Ishihara, M., Lamphire, M.S., Tanaka, N., Oishi, I., Aizawa, S., Matsuyama, T., Mak, T. W., Taki, S. and Taniguchi, T.
An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphosytes.
Nature 376, 596-599 (1995). - Suzuki, H., Kundig, M, T., Furlonger, C., Wakeham, A., Timms, E., Matsutama, T., Schmits, R., Simard, L.J.J., Ohashi, S.P., Griesser, H., Taniguchi, T., Paige, J.C., and Mak, W. T.
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptorβ.
Science 268, 1472-1476 (1995). - Fujii, H., Nakagawa, Y., Schindler, U., Kawahara, A., Niru, H., Gouilleux, F., Groner, B., Ihle, J. N., Minami, Y., Miyazaki, T., and Taniguchi, T.
Activation of Stat5 by interleukin 2 requires a carboxy1-terminal region of the interleukin 2 receptor βchain but is not essential for the proliferative signal transmission.
Proc. Natl. Acad. Sci. USA 92, 5482-5486 (1995). - Taniguchi, T.
Cytokine signaling through nonreceptor protein tyrosine kinases.
Science 268, 251-255 (1995). - Miyazaki, T., Liu, Z-J., Kawahara, A., Minami, Y., Yamada, K., Tsujimoto, Y., Barsoumian, E. L., Perlmutter, R. M. and Taniguchi, T.
Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc and lck cooperate in hematopoietic cell proliferation.
Cell 81, 223-231 (1995). - Uegaki, K., Shirakawa, M., Harada, H., Taniguchi, T. and Kyogoku, Y.
Secondary structure and folding topology of the DNA binding domain of interferon regulatory factor 2, as revealed by NMR spectroscopy.
FEBS Letters 359, 184-188 (1995). - Kawakami, T., Matsumoto, M., Sato, M., Harada, H., Taniguchi, T., and Kitagawa, M.
Possible involvement of the transcription factor ISGF3g in virus-induced expression of the IFN-βgene.
FEBS Letters 358, 225-229 (1995). - Minami, Y., Nakagawa, Y., Kawahara, A., Miyazaki, T., Sada, K., Yamamura, H. and Taniguchi, T.
Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor, possible link with the c-myc induction pathway.
Immunity 2, 89-100 (1995). - Uegaki, K., Shirakawa, M., Harada, H., Taniguchi, T. and Kyogoku, Y.
Unique structure of the DNA binding domain of interferon regulatory factor 2 determined by NMR spectroscopy.
Proc. Japan Acad. 70, 200-204 (1994). - Miyazaki, T., Kawahara, A., Fujii, H., Nakagawa, Y., Minami, Y., Liu, Z-J., Oishi, I., Silvennoinen, O., Witthuhn, B.A., Ihle, J.N., and Taniguchi, T.
Functional activation of Jak 1 and Jak3 by selective association with IL-2 receptor subunits.
Science 266, 1045-1047 (1994). - Harada, H., Kondo, T., Ogawa, S., Tamura, T., Kitagawa, M., Tanaka, N., Lamphier, M.S., Hirai, H., and Taniguchi, T.
Accelerated exon skipping of IRF-1 mRNA in human myelodysplasia; leukemia; a possible mechamism of tumor suppressor inactivation.
Oncogene 9 , 3313-3320 (1994). - Shibuya, H., Kofu, K., Yamada, K., Barsoumian, L. E., Perlmutter, M. R. and Taniguchi, T.
Functional dissection of p56lck a protein tyrosine kinase which mediates Interleukin-2-Induced activation of the c-fos gene.
Mol. Cell. Biol. 14, 5812-5819 (1994). - Tanaka, N., Ishihara, M., Taniguchi, T.
Suppression of c-myc or fos B-induced cell transformation of by the transcription factor IRF-1.
Cancer Letters 83, 191-196 (1994). - Kawahara, A., Minami, Y. and Taniguchi, T.
Evidence for a criticalrole for the cytoplasmic region of the Interleukin 2 (IL-2) receptorγchain in IL-2, IL-4, and IL-7 signaling.
Mol. Cell. Biol. 14, 5433-5440 (1994). - Minami, Y., Oishi, I., Liu, Z-J., Nakagawa, S., Miyazaki, T. and Taniguchi, T.
Signal transduction mediated by the reconstituted IL-2 receptor.
J. Immunol. 152, 5680-5690 (1994). - Kimura, T., Nakayama, K., Penninger, J., Kitagawa, M., Harada, H., Matsuyama, T., Tanaka, N., Kamijo, R., Vilcek, J., Mak, T. W., Taniguchi, T.
Involvement of the IRF-1 transcription factor in antiviral responses to interferons.
Science 264, 1921-1924 (1994). - Tanaka, N., Ishihara, M., Kitagawa, M., Harada, H., Kimura, T., Matsuyama, T., Lamphier, M. S., Aizawa, S., Mak, T. W. and Taniguchi, T.
Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF 1.
Cell 77, 829-839 (1994). - Yamanoto, H., Lamphier, M.S., Fujita, T.,Taniguchi, T. and Harada, H.
The oncogenic transcription factor IRF-2 possesses a transcriptional repression and a latent activation domain.
Oncogene 9, 1423-1428 (1994). - Kamijo, R., Harada, H., Matsuyama, T., Bosland, M., Gerecitano, J., Shapiro, D., Koh, S. I., Kimura, T., Green, J. S., Mak, T. W., Taniguchi, T., Vilcek, J.
Requirement for Transcription Factor IRF-1 in NO Synthase Induction in Macrophages.
Science 263, 1612-1615 (1994). - Harada, H., Takahashi, E., Itoh, S., Harada., K., Hori, T., and Taniguchi, T.
Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and (IRF-2) genes: Implications for a gene network in the interferon system.
Mol. Cell. Biol. 14, 1500-1509 (1994). - Kono, T., Minami, Y. and Taniguchi, T.
The interleukin-2 receptor complex and signal transduction: role of the β-chain.
Seminars in Immunol. 5, 299-307 (1993). - Matsuyama, T., Kimura, T., Kitagawa, M., Pfeffer, K., Kawakami, T., Watanabe, N., K dig, M. T., Amakawa, R., Kishihara, K., Wakaeham, A., Potter, J., Furlonger, L. C., Narendran, A., Suzuki, H., Ohashi, P. S., Paige, J. C., Taniguchi, T. and Mak, T. W.
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development.
Cell 75, 83-97 (1993). - Kobayashi, N., Nakagawa, S., Minami, Y., Taniguchi, T. and Kono, T.
Cloning andsequencing of the cDNA encoding a mouse IL-2 receptor γ.
Gene 130, 303-304 (1993). - Tanaka, N., Kawakami, T., and Taniguchi, T.
Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system.
Mol. Cell. Biol. 13, 4531-4538 (1993). - Taniguchi, T., and Minami, Y.
The IL-2/IL-2 receptor system: A current overview.
Cell 73, 5-8 (1993). - Kobayashi, N., Kono, T., Hatakeyama, M., Minami, Y., Miyazaki, T., Perlmutter, M.R., and Taniguchi, T.
Functional coupling of the src-family protein tyrosine kinases, p59fyn and p53/56lyn with the interleukin-2 receptor; Implications for redundancy and pleiotropism in cytokine signal transduction.
Proc. Natl. Acad. Sci. USA 90, 4201-4205 (1993). - Minami, Y., Kono, T., Miyazaki, T., and Taniguchi, T.
The IL-2 receptor complex: Its structure, function, and target genes.
Annu. Rev. Immunol. 11, 245-267 (1993). - Willman, C. L., Sever C. E., Pallavicini, M. G., Harada, H., Tanaka, N., Slovak, M. L., Yamamoto, H., Harada, K., Meeker, T. C., List, A. F., and Taniguchi, T.
Deletion of IRF 1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia.
Science 259, 968-971 (1993). - Harada H., Kitagawa, M., Tanaka,N., Yamamoto, H., Harada, K., Ishihara, M., and Taniguchi, T.
Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and-2.
Science 259, 971-974 (1993). - Minami, Y., Kono, T., Yamada, K., Kobayashi, N., Kawahara, A., Perlmutter, R. M., and Taniguchi, T.
Association of p56lck with IL-2 receptor β chain is critical for the IL-2 induced activation of p56lck.
EMBO J. , 12 759-768. (1993). - Tanaka, N., and Taniguchi, T.
Cytokine gene regulation: Regulatory cis-elements and DNA binding factors involved in the interferon system.
Adv. Immunol. 52, 263-281 (1992). - Minami, Y., Kono, T., Yamada, K., and Taniguchi, T.
The interleukin-2 receptors: Insights into a complex signalling mechanism.
Biochem. Biophys. Acta. 1114, 163 177 (1992). - Satoh, T., Minami, Y., Kono, T., Yamada, K., Kawahara, A., Taniguchi, T., and Kaziro, Y.
Interleukin 2-induced activation of Ras requires two domains of interleukin 2 receptor β subunit, the essential region for growth stimulation and Lck-binding domain.
J. Biol. Chem. 267, 25423-25427 (1992). - Shibuya, H., Irie, K., Ninomiya-Tsuji, J., Goebl, M., Taniguchi, T., and Matsumoto, K.
New human gene encoding a positive modulator of HIV Tat-mediated transactivation.
Nature 357, 700-702 (1992). - Shibuya, H., Yoneyama, M., Ninomiya-Tsuji, J., Matsumoto, K., and Taniguchi, T.
IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: Demonstration of a novel role for c-myc.
Cell 70, 57-67 (1992). - Nakanishi, K., Hirose, S., Yoshimoto, T., Ishizashi, H., Hiroishi, K., Tanaka, T., Kono, T., Miyasaka, M., Taniguchi, T.
Role and regulation of interleukin (IL)-2 receptorαandβchains in IL-2-driven B-cell growth.
Proc. Natl. Acad. Sci. USA 89, 3551-3555 (1992). - Tanaka, T., Tsudo, M., Karasuyama, H., Kitamura, F., Kono, T., Hatakeyama, M., Taniguchi, T., and Miyasaka, M.
A novel monoclonal antibody against murine IL-2 receptor β-chain: Characterization of receptor expression in normal lymphoid cells and EL 4 cells.
J. Immunol. 147, 2222-2228 (1992). - Hatakeyama, M., Kawahara, A., Mori, H., Shibuya, H., and Taniguchi, T.
c-fos gene induction by IL-2: Identification of the critical cytoplasmic regions within the IL-2 receptorβchain.
Proc. Natl. Acad. Sci. USA 89, 2022-2026 (1992). - Reis, L. F. L., Harada, H., Wolchok, J. D., Taniguchi, T., and Vilcek, J.
Critical role of a common transcription factor, IRF-1, in the regulation of IFN-βand IFN-inducible genes.
EMBO J. 11, 185-193 (1992). - Taniguchi, T., Hatakeyama, M., Minamoto, S., Kono, T., Mori, H., Okamoto, Y., and Shimizu, K.
Molecular analysis of human IL-2 and IL-2 receptors.
In: Drug Resiatances as A Biochemical Target in Cancer Chemotherapy (Academic Press, Inc) 211-222. (1992). - Miyazaki, T., Maruyama, M., Yamada, G., Hatakeyama, M. and Taniguchi, T.
The integrity of the conserved "WS motif" common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction.
EMBO J. 10, 3191-3197 (1991). - Itoh, S., Harada, H., Nakamura, Y., White, R., and Taniguchi, T.
Assignment of the human interferon regulatory factor-1 (IRF1) gene to chromosome 5q23-q31.
Genomics 10, 1097-1099 (1991). - Watanabe, N., Sakakibara, J., Hovanessian, A., Taniguchi, T., and Fujita, T.
Activation of IFN-β promoter element by IRF-1 requires a pos-translational event in addition to IRF-1 synthesis.
Nucleic Acids Res. 19, 4421-4428 (1991). - Taniguchi, T., Fujita, T., Harada, H., Sakakibara, J., Watanabe, N., and Kimura, T.
Molecular basis for the regulation of type I IFN system.
In: Serono Symposia Publications from Raven Press Vol. 82. The Status of Differentiation Therapy of Cancer vol. II 215-220. Eds. S. Waxman G.B. Rossi , F Takaku. (1991). - Pleiman, C. M., Gimpel, S. D., Park, L. S., Harada, H., Taniguchi, T., and Ziegler, S. F.
Organization of the murine and human interleukin-7 receptor genes: Two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter.
Mol. Cell. Biol. 11, 3052-3059 (1991). - Taniguchi, T., Fujita, T., Harada, H., Sakakibara, J.,Watanabe, N.,and Kimura T.
Cytokine gene expression: Molecular basis for the regulation of type Iinterferon system.
In: Cytokine Interactions and their Control. Edited by A. Baxterand R. Ross. (John Wiley & Sons Ltd.) , 39-50 (1991). - Hatakeyama, M., Kono, T., Kobayashi, N., Kawahara, A., Levin, S. D., Perlmutter, R. M., and Taniguchi, T.
Interaction of the IL-2 receptor with the src-family kinase p56lck: Identification of novel intermolecular association.
Science 252, 1523-1528 (1991). - Taniguchi, T., Fujita, T., Harada, H., Sakakibara, J., and Watanabe, N.
Regulation of cellular responses by cytokines: Positive and negative transcription factors affecting the interferon system.
In: Origins of Human Cancer: A Comprehensive Review (Cold Spring Harbor Laboratory Press), 501 (1991). - Tanaka, T., Tsudo, M., Karasuyama, H., Toyama, N., Hatakeyama, M., Taniguchi, T., and Miyasaka, M.
Signal transduction through the human IL-2 receptor β-chain expressed in IL-6-dependent mouse B cell hybridoma.
Int. Immunol. 3, 105-108 (1991). - Yamada, G., Ogawa, M., Akagi, K., Miyamoto, H., Nakano, N., Itoh, S., Miyazaki, J., Nishikawa, S., Yamamura, K., and Taniguchi, T.
Specific depletion of the B cell population induced by aberrant expression of human IRF-1 (interferon regulatory factor-1) gene in transgenic mice.
Proc. Natl. Acad. Sci. USA 88, 532-536 (1991). - Mori, H., Barsoumian, E. L., Hatakeyama, M., and Taniguchi, T.
Signal transduction by interleukin 2 receptorβchain: importance of the structural integrity as revealed by site directed mutagenesis and generation of chimeric receptors.
Int. Immunol. 3, 149-156 (1990). - Okamoto, Y., Minamoto, S., Shimizu, K., Mogami, H. and Taniguchi, T.
Interleukin 2 receptorβchain expressed in an oligodendroglioma line binds interleukin 2 and delivers growth signal.
Proc. Natl. Acad. Sci. USA 87, 6584-6588 (1990). - Reis, L. F. L., Fujita, T., Lee, T. H., Taniguchi, T. and Vilcek, J.
TNF and IL-1 induce mRNAs for the transcription factors IRF-1 and IRF-2: Possible roles in the regulation of IFN-βexpression.
Molecular and Cellular Biology of Cytokines (Wiley-Liss Inc.), 1-6 (1990). - Tsudo, M., Karasuyama, H., Kitamura, F., Tanaka, T., Kubo, S., Yamamura, Y., Tamatani, T., Hatakeyama, M., Taniguchi, T. and Miyasaka, M.
The IL-2 Receptor βchain (p70): Ligand binding ability of the cDNA-encoding membrane and secreted forms.
J. Immunol. 145, 599-606 (1990). - Harada, H., Willison, K., Sakakibara, J., Miyamoto, M., Fujita, T. and Taniguchi, T.
Absence of the type I IFN system in EC cells: Transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated.
Cell 63, 303-312 (1990). - Shibuya H., Yoneyama, M., Nakamura, Y., Harada, H., Hatakeyama, M., Minamoto, S., Kono, T., Doi, T., White, R. and Taniguchi, T.
The human interleukin-2 receptor β-chain gene: Genomic organization, promoter analysis and chromosomal assignment.
Nucleic Acids Res. 18, 3697 (1990). - Hatakeyama, M. and Taniguchi, T.
Interleukin-2.
In: Handbook of Experimental Pharmacology Vol.95/I; Peptide Growth Factors and Their Receptors I M. B. Spron & A. B. Roberts eds. (Springer-Verlag Berlin Heidelberg) , 523-540 (1990). - Kono, T., Doi, T., Yamada, G., Hatakeyama, M., Minamoto, S. Tsudo, M., Miyasaka, M., Miyata, T. and Taniguchi, T.
Murine interleukin 2 recptor βchain: Dysregulated gene expression in lymphoma line EL-4 caused by a promoter insertion.
Proc. Natl. Acad. Sci. USA 87, 1806-1810 (1990). - Taniguchi, T., Hatakeyama, M., Minamoto, S., Kono, T., Doi, T., Tsudo, M., Miyasaka, M. and Miyata, T.
Interleukin-2 receptorβchain: Molecular cloning and functional expression of the human cDNA.
Cold Spring Harb. Symp. Quant. Biol. Vol. LIV, 689-694 (1989). - Taniguchi, T., Hatakeyama, M., Minamoto, S., Kono, T., Doi, T., Tsudo, M. and Miyasaka, M.
Molecular analysis of the interleukin-2 receptor complex: Expression of the human αandβchain cDNAs.
Progress in Immunology Vol VII F. Melchers et al. eds. Berlin , 627-632 (1989). - Itoh, S., Harada, H., Fujita, T., Mimura, T. and Taniguchi, T.
Sequence of a cDNA coding for human IRF-2.
Nucleic Acids Res. 17, 8372 (1989). - Maruyama, M., Fujita, T. and Taniguchi, T.
Sequence of a cDNA coding for human IRF-1.
Nucleic Acids Res. 17, 3292 (1989). - Kuga, T., Fujita, T. and Taniguchi, T.
Nucleotide sequence of the mouse interferon-βgene.
Nucleic Acids Res. 17, 3291 (1989). - Taniguchi, T.
Regulation of interferon-βgene: Structure and function of cis-elements and trans-acting factors.
J. Interferon Res. 9, 633-640 (1989). - Doi, T., Hatakeyama, M., Minamoto, S., Kono, T., Mori, H. and Taniguchi, T.
Human interleukin 2 (IL 2) receptorβchain allows transduction of IL 2-induced proliferation signal(s) in a murine cell line.
Eur. J. Immunol. 19, 2375-2378 (1989). - Hatakeyama, M., Mori, H., Doi, T. and Taniguchi, T.
A restricted cytoplasmic region of IL-2 receptorβchain is essential for growth signal transduction but not for ligand binding and internalization.
Cell 59, 837-845 (1989). - Shibuya, H. and Taniguchi, T.
Identification of multiple cis-elements and trans-acting factors involved in the induced expression of human IL-2 gene.
Nucleic Acids Res. 17, 9173-9184 (1989). - Shibuya, H., Yoneyama, M. and Taniguchi, T.
Involvement of a common transcription factor in the regulated expression of IL-2 and IL-2 receptor genes.
Int. Immunol. 1, 43-49 (1989). - Harada, H., Fujita, T., Miyamoto, M., Kimura, Y., Maruyama, M., Furia, A., Miyata, T. and Taniguchi, T.
Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes.
Cell 58, 729-739 (1989). - Hatakeyama, M., Tsudo,M., Minamoto, S., Kono, T., Doi, T., Miyata, T., Miyasaka, M. and Taniguchi, T.
Interleukin-2 receptorβchain gene: Generation of three receptor forms by cloned human αandβchain cDNA's.
Science 244, 551-556 (1989). - Doi, T., Hatakeyama, M., Itoh, S. and Taniguchi, T.
Transient induction of IL-2 receptor in cultured T cell lines by HTLV-1 LTR-linked tax-1 gene.
EMBO J. 8, 1953-1958 (1989). - Fujita, T., Miyamoto, M., Kimura, Y., Hammer, J. and Taniguchi, T.
Involvement of a cis-element that binds an H2TF-1/NFkB like factor(s) in the viurs-induced interferon-βgene expression.
Nucleic Acids Res. 17, 3335-3346 (1989). - Fujita, T., Kimura, Y., Miyamoto, M., Barsoumian, E. L. and Taniguchi, T.
Induction of endogenous IFN-αand IFN-βgene by a regulatory transcription factor, IRF-1.
Nature 337, 270-272 (1989). - Fujita, T., Reis, L.F.L., Watanabe, N., Kimura, Y., Taniguchi, T., and Vilcek, J.
Induction of the transcription factor IRF-1 and interferon-βmRNAs by cytokines and activators of second-messenger pathways.
Proc. Natl. Acad. Sci. USA 86, 9936-9940 (1989). - Yamasaki, K., Taga, T., Hirata, Y., Yawata, H., Kawanishi, Y., Seed, B., Taniguchi, T., Hirano, T., and Kishimoto, T.
Molecular structure of interleukin 6 receptor.
In: Proceedings of the Japan Academy 64 Ser. B , 209-210 (1988). - Fujita, T., Sakakibara, J., Sudo, Y., Miyamoto, M., Kimura, Y., and Taniguchi, T.
Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-β gene regulatory elements.
EMBO J. 7, 3397-3405 (1988). - Taniguchi, T., Fujita, T., Yamada, G., Miyamoto, M., Harada, H., Kimura, Y., Maruyama, M. and Shibuya, H.
Cytokine gene expression: Regulation in the type I IFN and the IL-2 systems.
In: The Biology of the Interferon System 1988 Kawade Y. & Kobayashi S. eds. Kodansha Scientific , 3-10 (1988). - Tagawa, S., Hatakeyama, M., Shibano, M., Taniguchi, T. and Kitani, T.
The expression of the p75 subunit of interleukin 2 receptor in Tac negative leukemic cells of two patients with large granular lymphocytic leudemia.
Blood 71, 1161-1194 (1988). - Buchan, G., Barett, K., Fujita, T., Taniguchi, T., Maini, R. and Feldmann, M.
Detection of activated T cell products in the rheumatoid joint using cDNA probes to interleukin-2 (IL-2) IL-2 receptor and IFN-γ.
Clin. Exp. Immunol. 71, 295-301 (1988). - Yamada, G., Hatakeyama, M., Fujita, T. and Taniguchi, T.
Molecular biology of the interleukin-2 system.
Gann Monogr. Canc. Res. 34, 167-175 (1988). - Yamasaki, K., Taga, T., Hirata, Y., Yawata, H., Kawanishi, Y., Seed, B., Taniguchi, T., Hirano, T. and Kishimoto, T.
Cloning and expression of the human interleukin-6 (BSF 2/IFNβ2) receptor.
Science 241, 825-828 (1988). - Miyamoto, M.,Fujita, T., Kimura, Y., Maruyama, M., Harada, H., Sudo, Y., Miyata, T. and Taniguchi, T.
Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements.
Cell 54, 903-913 (1988). - Hatakeyama, M. and Taniguchi, T.
Dysregulation of growth factor receptor system in cellular transformation.
Jpn. J. Cancer Res. 79, 885-901 (1988). - Taniguchi, T.
Regulation of cytokine gene expression.
Annu. Rev. Immunol. 6, 439-464 (1988). - Yamada, G., Kitamura, Y., Sonoda ,H., Harada, H., Taki, S., Mulligan, R.C., Osawa, H., Diamantstein, T., Yokoyama, S. and Taniguchi, T.
Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity.
EMBO J. 6, 2705-2709 (1987). - Hatakeyama, M., Doi, T., Kono, T., Maruyama, M., Minamoto, S., Mori, H., Kobayashi, M., Uchiyama, T. and Taniguchi, T.
Transmembrane signaling of interleukin 2 receptor: Conformation and function of human interleukin 2 receptor (p55)/insulin receptor chimeric molecules.
J. Exp. Med. 166, 362-375 (1987). - Fujita, T., Shibuya, H., Hotta, H., Yamanishi, K. and Taniguchi, T.
Interferon-β gene regulation: Tandemly repeated sequences of a synthetic 6bp oligomer function as a virus inducible enhancer.
Cell 49, 357-367 (1987). - Maruyama, M., Shibuya, H., Harada, H., Hatakeyama, M., Seiki, M., Fujita, T., Inoue, J-I., Yoshida, M. and Taniguchi, T.
Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.
Cell 48, 343-350 (1987). - Sato, T., Matsui, H., Shibahara S., Kobayashi T., Morinaga, Y., Kashima, N., Yamasaki, S., Hamuro, J. and Taniguchi, T.
New approaches for the high-level expression of human interleukin-2 cDNA in Escherichia coli.
J. Biochem. 101, 525-534 (1987). - Taniguchi, T.
B.C., D.C., and A.C. of an interferon gene.
J. Interferon Res. 7, 481-485 (1987). - Tanaka, T., Saiki, O., Doi, S., Hatakeyama, M., Doi, T., Kono, T., Mori, H., Fujii, M., Sugamura, K., Negoro, S., Taniguchi, T. and Kishimoto, S.
Functional interleukin 2 receptors on B cells lacking Tac antigens.
Eur. J. Immunol. 17, 1379-1382 (1987). - Shibuya, H., Harada, H., Maruyama, M., Fujita, T., Seiki, M., Inoue, J., Yoshida, M., Hatakeyama, M. and Taniguchi, T.
Two step activation of the interleukin-2 autocrine loop may be involved in ATL development.
In: Molecular Basis of Lymphokine Action David R. Webb Carl W. Pierce and Stanley Cohen eds. The Humana Press New Jersey U.S.A. , 161-169 (1987). - Hatakeyama, M., Minamoto, S., Mori, H. and Taniguchi, T.
Structure and Function of the human interleukin-2 receptor.
In: Oncogenes and Growth Control P. Kahn & T. Graf eds. Springer-Verlag Berlin Heidelberg , 129-134 (1986). - Taniguchi, T., Fujita ,T., Hatakeyama, M., Mori, H., Matsui, H., Sato, T., Hamuro, J., Minamoto, S., Yamada, G. and Shibuya, H.
Interleukin-2 and its receptor: Structure and functional expression of the genes.
Cold Spring Harb. Symp. LI, 577-586 (1986). - Hirano, T., Yasukawa, K., Harada, H., Taga, T., Watanabe, Y., Matsuda, T., Kashiwamura, S., Nakajima, K., Koyama, K., Iwamatsu, A., Tsunasawa, S., Sakiyama, F., Matsui, H., Takahara, Y., Taniguchi, T. and Kishimoto, T.
Complementary DNA for anovel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin.
Nature 324, 73-76 (1986). - Kuga, T., Hattori, S., Yoshida, M. and Taniguchi, T.
Expression of human T-cell leukemia virus type I envelope protein in Saccharomyces cerevisiae.
Gene 44, 337- 340 (1986). - Yamada, G., Fujita, T., Hatakeyama, M. and Taniguchi, T.
Molecular biology of interleukin-2 and its receptor: The current status.
In: Progress in Immunology VI B. Cinader & R. Miller eds. Academic Press Inc. Toronto , 469-475 (1986). - Hatakeyama, M.,Minamoto, S. and Taniguchi, T.
Intracytoplasmic phosphorylation sites of Tac antigen (p55) are not essential for the conformation, function and regulation of the human interleukin 2 receptor.
Proc. Natl. Acad. Sci. USA 83, 9650-9654 (1986). - Hasegawa, K.,Maruyama, M.,Fujita, T., Ohashi, T., Hatakeyama, M., Minamoto, S.,Yamada, G. and Taniguchi, T.
Structure and regulation of the genes encoding interleukin-2 and its receptor.
In: Regulation of Immune Gene Expression Feldmann M. & McMichael A. eds. The Humana Press Inc. Clifton U.S.A. , 85-93 (1986). - Fujita, T., Shibuya, H., Ohashi, T. Yamanishi, K. and Taniguchi, T.
Regulation of human interleukin-2 gene.: Functional DNA sequences in the 5' flanking region for the gene expression in activated T lymphocytes.
Cell 46, 401-407 (1986). - Taniguchi, T., Matsui, H., Fujita, T., Hatakeyama, M., Kashima, N., Fuse, A., Hamuro, J., Nishi-Takaoka, C. and Yamada, G.
Molecular analysis of the interleukin-2 system.
Immunol. Rev. 92, 121-133 (1986). - Seiki, M., Hikikoshi, A., Taniguchi, T., Yoshida, M.
Expression of the pX gene of HTLV-1: General splicing mechanism in the HTLV family.
Science 228, 1532-1534 (1985). - Matsui, H., Fujita, T., Nishi-Takaoka, C., Hamuro, J. and Taniguchi, T.
Molecular cloning and expression of the human interleukin 2 gene.
Lymphokines (E. Picked.) Academic Press Inc. 12, 1-12 (1985). - Hatakeyama, M., Minamoto, S., Uchiyama, T., Hardy, R. R., Yamada, G. and Taniguchi, T.
Reconstitution of functional receptor for human interleukin-2 in mouse cells.
Nature 318, 467-470 (1985). - Taniguchi, T., Fujita, T., Matsui, H., Kashima, N., Yoshimoto, R., Hamuro, J. and Nishi-Takaoka, C.
Molecular cloning, structural analysis and expression of the human interleukin-2 gene.
In: T cell Clones Research Monographs in Immunology 8 von Boehmer H. & Haas W. eds. Elsevier Amsterdam , 69-78 (1985). - Fujita, T., Ohno, S., Yasumitsu, H. and Taniguchi, T.
Delimitation and properties of DNA sequences required for the regulated expression of human interferon-β gene.
Cell 41, 489-496 (1985). - Taniguchi, T., Fuse, A., Nishi-Takaoka, C., Yamada, G., Hasegawa, K., Fujita, T., Kashima, N., Matsui, H. and Hamuro, J.
Structure and organization of the murine interleukin-2 gene.
In: Cellular and Molecular Biology of Lymphokines Sorg C. & Schimpl A. eds. Academic press Orlando U.S.A. , 587-593 (1985). - Shiroza, T., Nakazawa, K., Tashiro, N., Yamane, K., Yanagi, K., Yamasaki, M., Tamura, G., Saito, H., Kawade, Y. and Taniguchi, T.
Synthesis and secretion of biologically active mouse interferon-γ using a Bacillus subtilis a-amylase secretion vector.
Gene 34, 1-8 (1985). - Nishi, T., Fujita, T., Nishi-Takaoka, C., Saito, A., Matsumoto, T., Sato, M. Oka, T., Itoh, S., Yip, Y. K., Vilcek, J. and Taniguchi, T.
Cloning and expression of a novel variant of human interferon-g cDNA.
J. Biochem. 97, 153-159 (1985). - Kashima, N., Nishi-Takaoka, C., Fujita, T., Taki, S., Yamada, G., Hamuro, J. and Taniguchi, T.
Unique structure of murine interleukin-2 as deduced from cloned cDNAs.
Nature 313, 402-404 (1985). - Fuse, A., Fujita, T., Yasumitsu, H., Kashima, N., Hasegawa, K. and Taniguchi, T.
Organization and structure of the mouse interleukin-2 gene.
Nucleic Acids Res. 12, 9323-9331 (1984). - Shows, T., Eddy, R., Haley, L., Byers, M., Henry, M., Fujita, T., Matsui, H. and Taniguchi, T.
Interleukin 2 (IL-2) is assigned to human chromosome 4.
Somat. Cell Mol. Genet. 10, 315-318 (1984). - Itoh, S., Mizukami, T., Matsumoto, T., Nishi, T., Saito, A., Oka, T., Furuya, A., Takaoka, C. and Taniguchi, T.
Efficient expression in Escherichia coli of a mature and a modified human interferon-β.
DNA 3, 157-165 (1984). - Taniguchi, T., Ohno, S., Nishi, T., Itoh, S. and Takaoka, C.
Expression of the human interferon-β1 gene in heterologous host cells.
In: Humoral Factors in Host Defense Yamamura Y. et al. eds. (Academic Press) , 131-139 (1983). - Taniguchi, T., Matsui, H., Fujita, T., Takaoka, C., Kashima, N., Yoshimoto, R. and Hamuro, J.
Structure and expression of human interleukin-2 gene.
Progress in Immunology (Academic Press) V, 273-277 (1983). - Nishi, T., Sato, M., Saito, A., Itoh, S., Takaoka, C. and Taniguchi, T.
Construction and application of a novel plasmid vector for direct expression of foreign genes in Escherichia coli; ATG vector.
DNA 2, 265-273 (1983). - Higashi, Y., Sokawa, Y., Watanabe, Y., Kawade, Y., Ohno, S., Takaoka, C. and Taniguchi, T.
Structure and expression of a cloned cDNA for mouse interferon-β.
J. Biol. Chem. 258, 9522-9529 (1983). - Fujita, T., Takaoka, C., Matsui, H. and Taniguchi, T.
Structure of the human interleukin-2 gene.
Proc. Natl. Acad. Sci. USA 80, 7437-7441 (1983). - Ohno, S. and Taniguchi, T.
The 5'-flanking sequence of human interferon-β1 gene is responsible for viral induction of transcription.
Nucleic Acids Res. 11, 5403-5412 (1983). - Taniguchi, T., Matsui, H., Fujita, T., Takaoka, C., Kashima, N., Yoshimoto, R. and Hamuro, J.
Structure and expression of a cloned cDNA for human interleukin-2.
Nature 302, 305-310 (1983). - Taniguchi, T., Ohno, S., Fujii-Kuriyama, Y. and Takaoka, C.
Studies on a human interferon-b gene.
In: The Clinical Potential of Interferons (Univ. of Tokyo Press) , 341-351 (1982). - Taniguchi, T., Ohno, S. and Takaoka, C.
Expression of the cloned genes for human interferon-b in E.coli and in cultured mouse cells.
In: Interferons (Academic Press) , 15-25 (1982). - Ohno, S. and Taniguchi, T.
Inducer-responsive expression of the cloned human interferon-βgene introduced into cultured mouse cells.
Nucleic Acids Res. 10, 967-977 (1982). - Fujii-Kuriyama, Y., Taniguchi, T., Mizukami, Y., Sakai, M., Tashiro, Y. and Muramatsu, M.
Construction and identification of a hybrid plasmid containing DNA sequence complementary to phenobarbital-inducible cytochromoe P-450 messenger RNA form rat liver.
J. Biochem. 89, 1869-1879 (1981). - Taniguchi ,T., Pang, R. H. L., Yip, Y. K., Henriksen, D. and Vilcek, J.
Partial characterization of γ(immune) interferon mRNA extracted from human lymphocytes.
Proc. Natl. Acad. Sci. USA 78, 3469-3472 (1981). - Ohno, S. and Taniguchi, T.
Structure of a chromosomal gene for human interferon-β.
Proc. Natl. Acad. Sci. USA 78, 5305-5309 (1981). - Taniguchi, T., Guarente, L., Roberts, T. M., Kimelman, D., Douhan III, J. and Ptashne, M.
Expression of the human fibroblast interferon gene in E.coli.
Proc. Natl. Acad. Sci. USA 77, 5230-5233 (1980). - Taniguchi, T., Mantei, N., Schwarzstain, M., Nagata, S., Muramatsu, M. and Weissmann, C.
Human leukocyte and fibroblast interferons are structurally related.
Nature 285, 547-549 (1980). - Taniguchi, T., Ohno, S., Fujii-Kuriyama, Y. and Muramatsu, M.
The nucleotide sequence of human fibloblast interferon cDNA.
Gene 10, 11-15 (1980). - Taniguchi, T., Fujii-Kuriyama, Y. and Muramatsu, M.
Molecular cloning of human interferon cDNA.
Proc. Natl. Acad. Sci. USA 77, 4003-4006 (1980). - Taniguchi, T., Sakai, M., Fujii-Kuriyama, Y., Muramatsu, M., Kobayashi, S.and Sudo,T.
Construction and identification of a bacterial plasmid containing the human fibroblast interferon gene sequence.
Proc. Jpn. Acad. 55B, 464-469 (1979). - Weissmann, C., Nagata, S., Taniguchi, T., Weber, H. and Meyer, F.
The use of site directed mutagenesis in reversed genetics.
Genetic Engineering (Plenum Press) 1, 133-150 (1979). - Weissmann, C., Mantei, N., Boll, W., Weaver, R. F., Wilkie, N., Clements, B., Taniguchi, T., van Ooyen, A., van den Berg, J., Fried M. and Murray, K.
Expression of cloned viral and chromosomal plasmid-linked DNA in cognate host cells.
In: From gene to protein: Information transfer in normal and abnormal cells. 1th Miami Winter Symp. Academic Press , 99-132 (1979). - Taniguchi, T. and Weissmann, C.
Escherichia coli ribosomes bind to non-initiator sites of Qb RNA in the absence of formylmethionyl-tRNA.
J. Mol. Biol. 128, 481-500 (1979). - Weissmann, C., Weber, H., Taniguchi, T., Muler, W. and Meyer, F.
Reversed genetics: a new approach to the elucidation of structure-function relationship.
In: Human Genetics Possibilities and Realities CIBA Found. Sympo. No.66 Excerpta Medica Amsterdam , 47-61 (1979). - Weissmann, C., Weber, H., Taniguchi, T., Muler, W. and Meyer, F.
Application of site-directed mutagenesis to RNA and DNA genomes.
Biochem. Soc. Sympo. (London) 44 , 43-55 (1979). - Weber, H., Taniguchi, T., Muler, W., Meyer, F. and Weissmann, C.
Application of site-directed mutagenesis to RNA and DNA genomes.
Cold Spring Harb. Symp. Quant. Biol. 43, 669-677 (1978). - Weissmann, C., Weber, H., Taniguchi, T., Muler, W. and Meyer, F.
Site-directed mutagenesis as a tool in genetics: Application to RNA and DNA genomes.
In: Genetic Engineering Boyer H.W. and Nicosia S. eds. Elsevier North-Holland Biomedical Press , 65-76 (1978). - Taniguchi, T. and Weissmann, C.
Inhibition of Qb RNA 70S ribosome initiation complex formation by an oligonucleotide complementary to the 3' terminal region of E.coli 16S ribosomal RNA.
Nature 275, 770-772 (1978). - Taniguchi, T., Palmeri, M. and Weissmann, C.
Qb DNA-containing hybrid plasmids giving rise to Qb phage formation in the bacterial host.
Nature 274, 223-228 (1978). - Taniguchi, T. and Weissmann, C.
Site-directed mutations in the initiator region of the bacteriophage Qb coat cistron and their effect on ribosome binding.
J. Mol. Biol. 118, 533-565 (1978). - Weissmann, C., Taniguchi, T., Domingo, E., Sabo, D. and Flavell, R.A.
Site-directed mutagenesis as a tool in genetics.
In: Frontiers in Physicochemical Biology Academic Press Inc. N.Y., 167-182 (1978). - Domingo, E., Sabo, D., Taniguchi, T. and Weissmann, C.
Nucleotide sequence heterogeneity of an RNA phage population.
Cell 13, 735-744 (1978). - Weissmann, C., Taniguchi, T., Domingo, E., Sabo, D. and Flavell, R. A.
Site-directed mutagenesis as a tool in genetics.
In: Miami Winter Symposia (Academic Press) 14, 11-36 (1977). - Taniguchi, T. and Libonati, M.
DNA-dependent RNA polymerase from the hepatopancreas of Octopus vulgaris Lam.
Comp. Biochem. Physiol. 52B, 269-276 (1975). - Taniguchi, T. and Libonati, M.
Action of ribonuclease BS-1 on a DNA-RNA hybrid.
Biochem. Biophys. Res. Comm. 58, 280-286 (1974). - Libonati, M., Taniguchi, T. and Leone, E.
Resistance of ribonuclease dimers to subtilisin.
Biochem. Biophys. Acta. 317, 160-163 (1973). - Taniguchi, T., Libonati, M. and Leone, E.
Azione della subtilisina sulla ribonucleasi BS-1.
Boll. Soc. Ital. Biol. Sper. XLVIII, 1115-1119 (1972).
